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A large number of proteinuria

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A large number of proteinuria+ is the leading clinical manifestation and rudimentary Pathophysiological mechanism of NS patients.A large number of proteinuria refers to adult urinary protein excretion larger than 3.5g per day. In normal physiological conditions, glomerular filtration membrane have molecular barrier and charge barrier. When the volume of crude urine protein increased and is far more than the proximal tubule absorption, a large number of proteinuria appear .On this basis, any factors increasing glomerular pressure and leading to high perfusion, high filtration(such as High blood pressure, high protein diet or a large number of infusion of plasma protein) can push urine protein out.

Article URL : http://www.sjzhospital.com/faq/2439.html

Article by : Shijiazhuang Kidney Disease Hospital

TAG:large,proteinuria,glomerular filtration

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