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Normal Urinary Protein Excretion

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Normal Urinary Protein Excretion

Healthy adults usually excrete between 80 and 150 mg of protein in their urine each day, including serum globulins and albumin. This is quite low because larger proteins are not able to pass through the glomerular membrane into the kidney and the majority of those that do are reabsorbed into the blood stream in the proximal tubule.

However, in some cases there may be an abnormality in the function of the glomerulus, proximal tubule or production of proteins, leading to the presence of excess protein in the urine.

Clinical proteinuria+ is classified as 0.5 g of protein or more excreted in a 24-hour period or with an albumin:creatinine ratio of 30 mg/mmol or more.

proteinuria+ is common in the adult population and its clinical significance can vary widely. A clear diagnostic process is needed to identify the cause of the findings and guide the treatment decisions.

A dipstick test is often the first indicator of proteinuria and the extent of protein in the urine can be further investigated with a 24-hour urine collection test. If the results are positive, other diagnostic tests may be required to establish the cause of proteinuria and aid in the management of the condition. Referral to a nephrologist may also be needed in some cases.

Article URL : http://www.sjzhospital.com/faq/2488.html

Article by : Shijiazhuang Kidney Disease Hospital

TAG:Protein,Excretion,Normal

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